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Somatic mutations in chromatin remodeler genes could modify the epigenomic landscape of CLL, but They can be unusual In this particular malignancy compared to other lymphoid neoplasms. CHD2 is mutated in 5% of CLL and seven% of MBL.75 The histone methyltransferase SETD2 and ARID1A are also mutated in a little proportion of sufferers. Of Take note,